diff --git a/overlay/opt/emcomm-tools/bin/et-audio b/overlay/opt/emcomm-tools/bin/et-audio
index 4aa9062..705f2eb 100755
--- a/overlay/opt/emcomm-tools/bin/et-audio
+++ b/overlay/opt/emcomm-tools/bin/et-audio
@@ -2,7 +2,7 @@
 #
 # Author  : Gaston Gonzalez
 # Date    : 31 October 2024
-# Updated : 5 October 2025
+# Updated : 9 October 2025
 # Purpose : Configures ET audio device with sane defaults
 #
 # Preconditions
@@ -10,6 +10,7 @@
 #
 # Postconditions
 # 1. ALSA settings set on ET audio device
+. /opt/emcomm-tools/bin/et-common
 
 usage() {
   echo "usage: $(basename $0) <command>"
@@ -48,10 +49,27 @@ update-config () {
 
        et-log "Updating audio device: '${ET_DEVICE_NAME}' (${FULL_AUDIO_DEVICE})' for ALSA PnP configuration."
 
+       # Handle audio settings specifically if defined in the radio configuration
+       AUDIO_INIT_SCRIPT=$(jq -r -e '.audio.script' ${ET_ACTIVE_RADIO_CONF})
+       if [[ $? -eq 0 ]]; then
+         et-log "Executing audio configuration script: ${AUDIO_INIT_SCRIPT}"
+
+	 CMD="${AUDIO_INIT_SCRIPT} ${AUDIO_CARD} ${AUDIO_DEVICE}"
+	 et-log "Running command: ${CMD}"
+	 ${CMD}
+
+	 if [[ $? -ne 0 ]]; then
+	   et-log "Audio init script ${AUDIO_INIT_SCRIPT} failed. Can't start application."
+	   notify-user "Audio init script failed. Can't start application."
+	   exit 1
+	 fi
+	 
+	 exit 0
+       fi
+
+       # Handle audio generically for most sound card interfaces
        case ${ET_DEVICE_NAME} in
          "DIGIRIG_MOBILE")
-	   # TODO: 92% is needed for the TX-500MP. Revisit approach for setting speaker
-	   #       out differently across radios definitions.
            # Unmute Speaker a set volume. Adjust if remote station can't decode you. Your TX controls.
            amixer -q -c ${AUDIO_CARD} sset Speaker Playback Switch 42% unmute
            # Unmute Mic
diff --git a/overlay/opt/emcomm-tools/conf/radios.d/audio/lab599-tx500mp.sh b/overlay/opt/emcomm-tools/conf/radios.d/audio/lab599-tx500mp.sh
new file mode 100755
index 0000000..9922176
--- /dev/null
+++ b/overlay/opt/emcomm-tools/conf/radios.d/audio/lab599-tx500mp.sh
@@ -0,0 +1,38 @@
+#!/bin/bash
+#
+# Author  : Gaston Gonzalez
+# Date    : 9 October 2025
+# Purpose : Audio settings specific to the Lab599 TX-500MP
+#
+# Preconditions
+# 1. Supported audio interface is connected and properly detected
+#
+# Postconditions
+# 1. ALSA settings set on ET audio device
+
+usage() {
+  echo "usage: $(basename $0) <ET audio card> <ET device name>"
+}
+
+if [[ $# -ne 2 ]]; then
+  usage
+  exit 1
+fi
+
+AUDIO_CARD=$1
+ET_DEVICE_NAME=$2
+
+# Unmute Speaker and set the volume to 81. Adjust if the remote station
+# can't decode you or if there is not output power on TX.
+amixer -q -c ${AUDIO_CARD} sset Speaker Playback Switch 92% unmute
+
+# Unmute Mic
+amixer -q -c ${AUDIO_CARD} sset Mic Playback Switch 52% unmute
+
+# Set "L/R Capture" to 19. Adjust if you can't decode received audio.
+amixer -q -c ${AUDIO_CARD} sset Mic Capture Switch 31% unmute
+
+# Disable Auto Gain Control
+amixer -q -c ${AUDIO_CARD} sset 'Auto Gain Control' mute
+
+et-log "Applied amixer settings for audio card ${AUDIO_CARD} on device ${ET_DEVICE_NAME}"
diff --git a/overlay/opt/emcomm-tools/conf/radios.d/lab599-tx500mp.json b/overlay/opt/emcomm-tools/conf/radios.d/lab599-tx500mp.json
index 63331ac..773d60e 100644
--- a/overlay/opt/emcomm-tools/conf/radios.d/lab599-tx500mp.json
+++ b/overlay/opt/emcomm-tools/conf/radios.d/lab599-tx500mp.json
@@ -8,6 +8,9 @@
     "ptt": "RTS",
     "pttOnly": "false"
   },
+  "audio": {
+    "script": "/opt/emcomm-tools/conf/radios.d/audio/lab599-tx500mp.sh"
+  },
   "notes": [
     "1. Set MENU 36 CAT PROTOCOL = TS2000",
     "2. Set MODE = DIGI",
diff --git a/scripts/install-emcomm-tools.sh b/scripts/install-emcomm-tools.sh
index 186544a..745ce6a 100755
--- a/scripts/install-emcomm-tools.sh
+++ b/scripts/install-emcomm-tools.sh
@@ -2,7 +2,7 @@
 #
 # Author  : Gaston Gonzalez
 # Date    : 6 October 2024
-# Updated : 1 November 2024
+# Updated : 9 October 2025
 # Purpose : Install EmComm Tools applications
 
 et-log "Installing EmComm Tools applications..."
@@ -18,6 +18,10 @@ chgrp -v -R $ET_GROUP $ET_HOME/conf/radios.d
 chmod -v 775 $ET_HOME/conf/radios.d
 chmod -v 664 $ET_HOME/conf/radios.d/*.json
 
+chgrp -v -R $ET_GROUP $ET_HOME/conf/radios.d/audio
+chmod -v 775 $ET_HOME/conf/radios.d/audio
+chmod -v 664 $ET_HOME/conf/radios.d/audio/*.sh
+
 chgrp -v -R $ET_GROUP $ET_HOME/conf/template.d/packet
 chmod -v 775 $ET_HOME/conf/template.d/packet
 chmod -v 664 $ET_HOME/conf/template.d/packet/*.conf